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Arterosil contains MonitumRS™ – a proprietary extract of rhamnan sulfate, a specialized sulfated polysaccharide derived from the rare green seaweed, Monostroma nitidum. Rhamnan sulfate is a powerful glycocalyx regenerating compound and has been reported to possess many cardiovascular health benefits
The rhamnan sulfate found in Arterosil has a similar chemical structure to heparan sulfate found abundantly in human endothelial glycocalyx, and may exert its biological activities by regenerating endothelial glycocalyx.
- Regulates vascular permeability and fluid balance due to the large size and negative charge of its glycosaminoglycans
- Provides a physical barrier against inadvertent adhesion of platelets and leukocytes to the vascular wall
- Regulates coagulation as many of mediators of coagulation pathway are buried inside the glycocalyx under normal physiological condition
- Functions as a mechano-sensor and transducer of the shear-force inside blood vessels to regulate the synthesis of nitric oxide (NO) in response to the blood flow